Why People Distrust Science. Another Example.

Right now there is another drug out there that certain people are ridiculing doctors for prescribing. Pretty soon that ridicule will turn to punishment. It was for hydroxychloroquine. Now I am hearing that pharmacies are being told NOT to fill the Rx for it. The drug is called Ivermectin.

I am not going to go into detail on this drug. But here is the FDA’s brilliant post:

And from this news item:

“There is absolutely no evidence that ivermectin is beneficial for COVID-19 prevention or treatment.”

I have always been told in medicine not to use the words always or never. The above quote was from our friend, and noble liar, Dr. Anthony Fauci. The above items are strong statements. They are also horseshit.

Here is a recent article in the American Journal of Therapeutics called Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19. Here is their abstract:

Abstract

Background: 

After COVID-19 emerged on U.S shores, providers began reviewing the emerging basic science, translational, and clinical data to identify potentially effective treatment options. In addition, a multitude of both novel and repurposed therapeutic agents were used empirically and studied within clinical trials.

Areas of Uncertainty: 

The majority of trialed agents have failed to provide reproducible, definitive proof of efficacy in reducing the mortality of COVID-19 with the exception of corticosteroids in moderate to severe disease. Recently, evidence has emerged that the oral antiparasitic agent ivermectin exhibits numerous antiviral and anti-inflammatory mechanisms with trial results reporting significant outcome benefits. Given some have not passed peer review, several expert groups including Unitaid/World Health Organization have undertaken a systematic global effort to contact all active trial investigators to rapidly gather the data needed to grade and perform meta-analyses.

Data Sources: 

Data were sourced from published peer-reviewed studies, manuscripts posted to preprint servers, expert meta-analyses, and numerous epidemiological analyses of regions with ivermectin distribution campaigns.

Therapeutic Advances: 

A large majority of randomized and observational controlled trials of ivermectin are reporting repeated, large magnitude improvements in clinical outcomes. Numerous prophylaxis trials demonstrate that regular ivermectin use leads to large reductions in transmission. Multiple, large “natural experiments” occurred in regions that initiated “ivermectin distribution” campaigns followed by tight, reproducible, temporally associated decreases in case counts and case fatality rates compared with nearby regions without such campaigns.

Conclusions: 

Meta-analyses based on 18 randomized controlled treatment trials of ivermectin in COVID-19 have found large, statistically significant reductions in mortality, time to clinical recovery, and time to viral clearance. Furthermore, results from numerous controlled prophylaxis trials report significantly reduced risks of contracting COVID-19 with the regular use of ivermectin. Finally, the many examples of ivermectin distribution campaigns leading to rapid population-wide decreases in morbidity and mortality indicate that an oral agent effective in all phases of COVID-19 has been identified.

Let’s let me make a few points here:

  • I am not pushing for ivermectin for everyone. I have no skin in the game.
  • Meta-analyses are not perfect but we use them for a lot of other drugs that are prescribed.
  • This research paper is NOT the end-all, be-all for ivermectin. But NO evidence, Dr Fauci?
  • I do not want people taking medicines without a doctor’s rx.
  • I do not vouch for this journal though I do know one of the authors.

My point in this blog post is that NO ONE should outwardly dismiss ivermectin. This is not about politics. This is about science. And this is why no one trusts science anymore. Why would the FDA and Fauci dismiss this drug? Are there ulterior motives? It now makes me wonder.

And now it even makes me distrust science as well, especially when it is represented by Fauci, the FDA, the CDC, and the WHO.

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